What Are The Four Stages of Mesothelioma Cancer?
One rare form of cancer is called Mesothelioma, a
malignant tumor in the mesothelial tissues of the lungs and the
abdomen, arising from the inhalation of asbestos. Its rarity is one of
the reasons why a lot of people are not aware of this kind of fatal
disease. In fact, many people die of Mesothelioma undiagnosed.
Although there is now a growing awareness of the hazards of asbestos
to health, still many have not heard of Mesothelioma and thus, have
not understood its nature, cause, signs and treatment. Even some
physicians find it hard to detect Mesothelioma because its symptoms
are akin to other diseases like lung cancer and pneumonia.
Furthermore, it takes decades for a patient who was exposed to
asbestos to develop Mesothelioma — fifty years, at most.
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Being unaware of Mesothelioma poses higher risks since
it deters diagnosis and treatment. A person undergoing treatment must
know the different stages of the cancer or the extent of the disease.
Chances of recovering from Mesothelioma and the kind of treatment
depend on the stage of the illness. There are basically two staging
systems used for Pleural Mesothelioma (lungs): TNM system and Brighan
system. These staging systems are also used in other kinds of cancers;
however, the first is commonly used. There is no established method in
determining the stage of the Peritoneal Mesothelioma cancer
(abdominal) so the TNM system is used. |
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There are three variables in the TNM system: tumor, lymph
nodes and metastasis. In the earliest stage of Mesothelioma, stage I, the
malignant Mesothelioma cells start to grow and multiply only one layer of
the pleura. The pleura is the membrane that encloses the lungs and lines the
wall of the chest cavity. However, there are some instances wherein the
pericardium (membrane that covers the heart) and diaphragm cover are already
affected. In this case, the cancer patient is still in stage I Mesothelioma.
In the second stage, the two layers of the pleura are already affected by
Mesothelioma. Take note, however, that in this stage, only one side of the
body is affected. Normally, the pleura produces only small amount of
lubricating fluid that allows easy expanding and contracting of the lungs.
The excess fluid is absorbed by the blood and the lymph vessels so there’s a
balance between the amount of fluid produced and removed. During the second
stage Mesothelioma, fluid starts to build up between the membrane of the
lungs and the membrane of the chest wall, resulting to pleural effusion. The
increase in the volume of fluid produced causes shortness of breath and
chest pain. Other Mesothelioma cancer patients experience dry and persistent
cough. Diagnosis of the pleural effusion is achieved through a chest x-ray.
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Stage III Mesothelioma means that the malignant cells
have already spread to the chest wall, esophagus and the lymph nodes
on one part of the chest. The patient may suffer severe pain near the
parts affected. When not treated immediately or when the Mesothelioma
patient doesn’t respond well to medication, the cancer may advance to
the fourth stage. The fourth stage Mesothelioma is formidable since at
this stage the Mesothelioma cells have penetrated into the bloodstream
and other organs in the body like the liver, the bones and the brain.
The lymph nodes on the other side of the chest may also be affected by
Mesothelioma in stage IV. |
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Brighan staging system, on the other hand, determines whether the Mesothelioma
can be surgically removed or not and whether the lymph nodes are affected or
not. In stage I Mesothelioma, the lymph nodes are not yet affected and the
patient can still recover through surgery. In stage II, surgery can still be
executed but some lymph nodes have already been infiltrated by the cancer cells.
In stage III, the heart and chest wall are already affected; thus, surgery is no
longer advisable. The lymph nodes in this stage, however, may or may not be
affected. In the final stage, stage IV Mesothelioma, cancer cells have already
gone to the bloodstream and other parts of the body like the heart, brain, bone
and liver. In most cases, a patient who has reached stage IV Mesothelioma only
has four to twenty-four months to live.
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